SEARCH

SEARCH BY CITATION

Keywords:

  • enantioselectivity;
  • enzyme catalysis;
  • high-throughput screening;
  • hydroxylation;
  • mass spectrometry
Thumbnail image of graphical abstract

Up to speed: An accurate, sensitive, high-throughput, and simple method for measuring the product ee value of enzyme-catalyzed hydroxylations (see scheme) is based on the use of enantiopure or enantioenriched deuterated substrates and mass spectrometric detection.