The Singapore National Research Foundation was gratefully acknowledged for financial support (NRF-RF2008-05). J.Z. thanks the Nanyang Technological University for a graduate student scholarship.
Synthesis of Cyclic Imides from Simple Diols†
Article first published online: 26 JUL 2010
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 49, Issue 36, pages 6391–6395, August 23, 2010
How to Cite
Zhang, J., Senthilkumar, M., Ghosh, S. and Hong, S. (2010), Synthesis of Cyclic Imides from Simple Diols. Angew. Chem. Int. Ed., 49: 6391–6395. doi: 10.1002/anie.201002136
- Issue published online: 19 AUG 2010
- Article first published online: 26 JUL 2010
- Manuscript Revised: 12 MAY 2010
- Manuscript Received: 12 APR 2010
- Singapore National Research Foundation. Grant Number: NRF-RF2008-05
- homogeneous catalysis;
- N-heterocyclic carbenes;
There′s something imide so strong: Cyclic imides were synthesized from simple diols with primary amines in a single step using an in-situ-generated ruthenium catalytic system. The atom-economical and operatively simple syntheses of succinimides, phthalimides, and glutarimides, which are important building blocks in natural products and drugs, was also demonstrated.