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Keywords:

  • azobenzene;
  • circular dichroism;
  • DNA;
  • G-quadruplexes;
  • photoregulation
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Bend and stretch… bend and stretch… An azobenzene derivative was used to induce reversible stretching and folding of G-quadruplex DNA upon photoirradiation (see picture). The G quadruplex formed in the presence of the trans isomer was dissociated by irradiation with UV light, and the resulting open oligomer was refolded into a G quadruplex under visible light. This nanodevice thus converts light directly into mechanical work.