This work was supported by the Non-equilibrium Energy Research Center (NERC), which is an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Award Number DE-SC0000989.
Nanoparticle Supracrystals and Layered Supracrystals as Chemical Amplifiers†
Article first published online: 13 JUL 2010
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 49, Issue 33, pages 5737–5741, August 2, 2010
How to Cite
Kowalczyk, B., Walker, David A., Soh, S. and Grzybowski, Bartosz A. (2010), Nanoparticle Supracrystals and Layered Supracrystals as Chemical Amplifiers. Angew. Chem. Int. Ed., 49: 5737–5741. doi: 10.1002/anie.201002295
- Issue published online: 28 JUL 2010
- Article first published online: 13 JUL 2010
- Manuscript Received: 18 APR 2010
- U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences. Grant Number: DE-SC0000989
Seeing is believing: Nanoparticle crystals and core–shell crystals detect and amplify the presence of chemical and enzymatic analytes. These crystals are made insoluble in water by cross-linking their surface with dithiols incorporating analyte-specific groups. Upon addition of an analyte, these groups are cut, and the “punctured” crystals liberate millions of individual, brightly colored NPs (see picture).