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Keywords:

  • alkynes;
  • homogeneous catalysis;
  • organocatalysis;
  • ruthenium;
  • synthetic methods
Thumbnail image of graphical abstract

Working together: The title reaction proceeds in the presence of a thiolate-bridged diruthenium complex (2) and a secondary amine (1) to give the corresponding propargylic alkylated products in excellent yields as a mixture of two diastereoisomers, each with high enantioselectivity. The two catalysts activate propargylic alcohols and aldehydes, respectively, and cooperatively promote the enantioselective reaction.