Microfluidic Gas-Flow Imaging Utilizing Parahydrogen-Induced Polarization and Remote-Detection NMR


  • This work was funded by the grants from the Academy of Finland (123847, 132132, and 116824), University of Oulu, RAS (5.1.1), RFBR (08-03-00661, 08-03-00539), SB RAS (67, 88), the program of support of leading scientific schools (NSh-7643.2010.3) and FASI (state contract 02.740.11.0262). I.V.K. thanks Prof. C. Bianchini and Dr. P. Barbaro (ICCOM-CNR, Sesto Fiorentino, Firenze, Italy) for providing the sample of catalyst [Rh(cod)(sulfos)]/SiO2.


original image

Sensitivity enhancement of several orders of magnitude provided by combining parahydrogen-induced polarization (PHIP) and remote-detection (RD) NMR techniques enables gas-flow visualization in microfluidic devices (see scheme). A 7700-fold reduction in the imaging time compared to the current state-of-the-art is achieved, and it can also be used to significantly improve the spatial resolution in such experiments.