Asymmetric Nanocatalysis: N-Heterocyclic Carbenes as Chiral Modifiers of Fe3O4/Pd nanoparticles


  • Generous financial support by the Alexander von Humboldt’Foundation (K.V.S.R.), the Deutsche Forschungsgemeinschaft (IRTG Münster-Nagoya; J.K.), and AstraZeneca is gratefully acknowledged. The research of F.G. has been supported by the Alfried Krupp Prize for Young University Teachers of the Alfried Krupp von Bohlen und Halbach Foundation. We thank Prof. Dr. Gerhard Wilde and Dr. Harald Rösner for TEM analyses, Prof. Dr. Uwe Karst and Michael Holtkamp for ICP-OES analyses, and Dr. Hubert Koller and Mark Weiß for determination of the BET surfaces.


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Superficial success: A chiral N-heterocyclic carbene (NHC*) is used to modify Fe3O4/Pd nanoparticles, which then catalyze asymmetric α-arylations. This successful synthesis of a heterogeneous catalyst and its appliation in asymmetric catalysis is in stark contrast to the simple immobilization of an established chiral homogeneous catalyst.