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Chemoselective Catalytic Hydrosilylation of Nitriles


  • This work was supported by the NSERC and OPIC. We are grateful to the CFI/OIT for a generous equipment grant.


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Well-behaved: The ruthenium complex [Cp(iPr3P)Ru(NCCH3)2]+ (Cp=cyclopentadienyl) catalyzes monohydrosilylation of nitriles (see scheme) with unprecedented tolerance of most common functional groups. The catalyst is easily synthesized starting from commercially available compounds, is air-stable, recyclable, and works under solvent-free conditions.