Copper-Promoted and Copper-Catalyzed Intermolecular Alkene Diamination

Authors


  • We are grateful for generous financial support from the National Institute of General Medical Sciences, National Institutes of Health (grant no. GM078383 and GM078383-S1-03). We thank William W. Brennessel and the Crystallographic Facility at the Chemistry Department of the University of Rochester for obtaining the X-ray structure of 12 f.

Abstract

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Simply copper: Copper(II)-promoted intra- and intermolecular olefin diaminations bring together two differently functionalized amines into a vicinal relationship. High diastereoselectivity was obtained with chiral alkenes and results of the asymmetric catalysis are promising.

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