This work was supported by the National Science Foundation and the Air Force Office of Scientific Research in the Gordon and Betty Moore Center of Physical Biology at Caltech.
Direct Structural Determination of Conformations of Photoswitchable Molecules by Laser Desorption–Electron Diffraction†
Article first published online: 16 AUG 2010
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 49, Issue 37, pages 6524–6527, September 3, 2010
How to Cite
Gahlmann, A., Lee, I.-R. and Zewail, Ahmed H. (2010), Direct Structural Determination of Conformations of Photoswitchable Molecules by Laser Desorption–Electron Diffraction. Angew. Chem. Int. Ed., 49: 6524–6527. doi: 10.1002/anie.201003583
- Issue published online: 1 SEP 2010
- Article first published online: 16 AUG 2010
- Manuscript Received: 12 JUN 2010
- conformational analysis;
- density functional calculations;
- electron diffraction;
- laser desorption;
Anfractuous paths: Electron diffraction reveals the involvement of multiple structures in the complex photochemistry of photoswitchable nitro-substituted 1,3,3-trimethylindolinobenzospiropyran. The spiropyran-to-merocyanine isomerization due to ring opening produces primarily the cis–trans–cis structure (see picture; red O, blue N, yellow C), while competing nonradiative pathways lead to other structures, namely the closed forms in their triplet and singlet ground states.