Asymmetric Cyclopropanation of Alkenes with Dimethyl Diazomalonate Catalyzed by Chiral Diene–Rhodium Complexes


  • This work has been supported by a Grant-in-Aid for Scientific Research (S) from the MEXT (Japan).


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Chiral tridentate ligand: A chiral diene–rhodium complex (1; see scheme) was found to catalyze the intermolecular asymmetric cyclopropanation of alkenes with dimethyl diazomalonate to give 1,1-cyclopropane diesters in good yields and with high enantioselectivity.