These authors contributed equally to this work.
Enzyme-Mediated Controlled Release Systems by Anchoring Peptide Sequences on Mesoporous Silica Supports†
Article first published online: 1 FEB 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 9, pages 2138–2140, February 25, 2011
How to Cite
Coll, C., Mondragón, L., Martínez-Máñez, R., Sancenón, F., Marcos, M. D., Soto, J., Amorós, P. and Pérez-Payá, E. (2011), Enzyme-Mediated Controlled Release Systems by Anchoring Peptide Sequences on Mesoporous Silica Supports. Angew. Chem. Int. Ed., 50: 2138–2140. doi: 10.1002/anie.201004133
We thank the Spanish Government (projects MAT2009-14564-C04, CB07/01/2012, and BIO2007 60066), the Generalitat Valencia (project PROMETEO/2009/016, PROMETEO/2010/005), and the CIBER-BBN for their support.
- Issue published online: 22 FEB 2011
- Article first published online: 1 FEB 2011
- Manuscript Revised: 27 DEC 2010
- Manuscript Received: 6 JUL 2010
- Spanish Government. Grant Numbers: MAT2009-14564-C04, CB07/01/2012, BIO2007 60066
- Generalitat Valencia. Grant Numbers: PROMETEO/2009/016, PROMETEO/2010/005
- controlled release;
- mesoporous materials;
- molecular gates;
Gated community: Peptides anchored to the surface of silica mesoporous supports by a valid procedure act as gatekeepers. In this way, “zero release” supports that selectively deliver the cargo in the presence of a suitable peptidase are obtained (see picture, red spheres: cargo, colored chains: peptides).