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Keywords:

  • bioorthogonal labeling;
  • click chemistry;
  • fluorescence imaging;
  • nanoparticles;
  • semiconducting polymers
Thumbnail image of graphical abstract

All aboard! A facile conjugation method allows covalent linking of functional molecules to semiconducting polymer dots for bioorthogonal labeling of cellular targets. Targeting of the polymer dots to newly synthesized proteins and glycoproteins in mammalian cells by click chemistry is highly efficient and specific.