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[Fe]-Hydrogenase Models Featuring Acylmethylpyridinyl Ligands


  • This work was supported by the EPFL and the Swiss National Science Foundation (project no. 200021_119663). We thank Prof. Rauchfuss (UIUC) for insightful discussions.


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Where is my iron? The synthesis, structure, and reactivity of small-molecule models of [Fe]-hydrogenase are described. These models feature the intriguing acylmethylpyridinyl ligands found exclusively in the enzyme.