1521-3773/asset/cover.gif?v=1&s=412bc65bdcb3f0e34a94f27c1c13e908726694d4 "Angewandte Chemie International Edition")
These authors contributed equally to this work.
1521-3773/asset/2002_left.gif?v=1&s=ac6b0d94a94d7ce7a210002b8096b42feffc0bcf)
1521-3773/asset/olbannercenter.gif?v=1&s=c083e1920cd41ed129901c116018eab93b5ad3c4)
1521-3773/asset/2002_right.gif?v=1&s=451042aa3415ae3ad0729984d26dee1866aca82e)
Review
Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis
Article first published online: 27 JUN 2011
DOI: 10.1002/anie.201004637
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Hartman, R. L., McMullen, J. P. and Jensen, K. F. (2011), Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis. Angew. Chem. Int. Ed., 50: 7502–7519. doi: 10.1002/anie.201004637
- †
These authors contributed equally to this work.
Publication History
- Issue published online: 5 AUG 2011
- Article first published online: 27 JUN 2011
- Manuscript Received: 28 JUL 2010
Funded by
- NIH
Keywords:
- continuous flow;
- flow chemistry;
- microfluidics;
- microreactors;
- synthetic chemistry
Abstract
The fine chemicals and pharmaceutical industries are transforming how their products are manufactured, where economically favorable, from traditional batchwise processes to continuous flow. This evolution is impacting synthetic chemistry on all scales—from the laboratory to full production. This Review discusses the relative merits of batch and micro flow reactors for performing synthetic chemistry in the laboratory.