These authors contributed equally to this work.
Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis
Article first published online: 27 JUN 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 33, pages 7502–7519, August 8, 2011
How to Cite
Hartman, R. L., McMullen, J. P. and Jensen, K. F. (2011), Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis. Angew. Chem. Int. Ed., 50: 7502–7519. doi: 10.1002/anie.201004637
- Issue published online: 5 AUG 2011
- Article first published online: 27 JUN 2011
- Manuscript Received: 28 JUL 2010
- continuous flow;
- flow chemistry;
- synthetic chemistry
The fine chemicals and pharmaceutical industries are transforming how their products are manufactured, where economically favorable, from traditional batchwise processes to continuous flow. This evolution is impacting synthetic chemistry on all scales—from the laboratory to full production. This Review discusses the relative merits of batch and micro flow reactors for performing synthetic chemistry in the laboratory.