Advertisement

Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis

Authors

  • Dr. Ryan L. Hartman,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 66-350, Cambridge, MA 02139 (USA), Fax: (+1) 617-258-8992
    2. Present address: Chemical and Biological Engineering, The University of Alabama, Box 870203, Tuscaloosa, AL 35487 (USA)
    Search for more papers by this author
    • These authors contributed equally to this work.

  • Jonathan P. McMullen,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 66-350, Cambridge, MA 02139 (USA), Fax: (+1) 617-258-8992
    2. Present address: Chemical Process Development and Commercialization, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ 07065 (USA)
    Search for more papers by this author
    • These authors contributed equally to this work.

  • Prof. Klavs F. Jensen

    Corresponding author
    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 66-350, Cambridge, MA 02139 (USA), Fax: (+1) 617-258-8992
    • Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 66-350, Cambridge, MA 02139 (USA), Fax: (+1) 617-258-8992
    Search for more papers by this author

Abstract

The fine chemicals and pharmaceutical industries are transforming how their products are manufactured, where economically favorable, from traditional batchwise processes to continuous flow. This evolution is impacting synthetic chemistry on all scales—from the laboratory to full production. This Review discusses the relative merits of batch and micro flow reactors for performing synthetic chemistry in the laboratory.

Ancillary