Removable Directing Groups in Organic Synthesis and Catalysis

Authors

  • Dr. Géraldine Rousseau,

    1. Institut für Organische Chemie und Biochemie, Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-Universität Freiburg, Albertstrasse 21, 79104 Freiburg i. Brsg. (Germany), Fax: (+49) 761-203-8715
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  • Prof. Dr. Bernhard Breit

    Corresponding author
    1. Institut für Organische Chemie und Biochemie, Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-Universität Freiburg, Albertstrasse 21, 79104 Freiburg i. Brsg. (Germany), Fax: (+49) 761-203-8715
    • Institut für Organische Chemie und Biochemie, Freiburg Institute for Advanced Studies (FRIAS), Albert-Ludwigs-Universität Freiburg, Albertstrasse 21, 79104 Freiburg i. Brsg. (Germany), Fax: (+49) 761-203-8715
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Errata

This article is corrected by:

  1. Errata: Corrigendum: Removable Directing Groups in Organic Synthesis and Catalysis Volume 50, Issue 22, 5007, Article first published online: 16 May 2011

Abstract

Directing groups have been widely used in recent years to achieve control over all aspects of reaction selectivity in a wide range of transformations involving transition-metal catalysis and organometallic reagents. In cases when the existing functional group within a substrate is unsuited to achieve efficient intramolecular delivery of a reagent or catalyst, the specific introduction of an appropriately designed removable reagent-directing group can be a solution to this problem. In this Review we give an overview of the state of the art in this area, including the stoichiometric and catalytic use of directing groups.

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