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Silica-Nanoparticle Coatings by Adsorption from Lysine–Silica-Nanoparticle Sols on Inorganic and Biological Surfaces

Authors

  • Nicole Atchison,

    1. Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455 (USA)
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    • These authors contributed equally to this work.

  • Dr. Wei Fan,

    1. Department of Chemical Engineering & Materials Science, University of Minnesota, Minneapolis, MN 55455 (USA), Fax: (+1) 612-626-7246
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    • These authors contributed equally to this work.

  • Damien D. Brewer,

    1. Department of Chemical Engineering & Materials Science, University of Minnesota, Minneapolis, MN 55455 (USA), Fax: (+1) 612-626-7246
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  • Dr. Manickam A. Arunagirinathan,

    1. Department of Chemical Engineering & Materials Science, University of Minnesota, Minneapolis, MN 55455 (USA), Fax: (+1) 612-626-7246
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  • Prof. Bernhard J. Hering,

    1. Schulze Diabetes Institute, Department of Surgery, University of Minnesota, Minneapolis, MN 55455 (USA)
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  • Prof. Satish Kumar,

    1. Department of Chemical Engineering & Materials Science, University of Minnesota, Minneapolis, MN 55455 (USA), Fax: (+1) 612-626-7246
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  • Prof. Klearchos K. Papas,

    1. Schulze Diabetes Institute, Department of Surgery, University of Minnesota, Minneapolis, MN 55455 (USA)
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  • Prof. Efrosini Kokkoli,

    Corresponding author
    1. Department of Chemical Engineering & Materials Science, University of Minnesota, Minneapolis, MN 55455 (USA), Fax: (+1) 612-626-7246
    • Department of Chemical Engineering & Materials Science, University of Minnesota, Minneapolis, MN 55455 (USA), Fax: (+1) 612-626-7246
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  • Prof. Michael Tsapatsis

    Corresponding author
    1. Department of Chemical Engineering & Materials Science, University of Minnesota, Minneapolis, MN 55455 (USA), Fax: (+1) 612-626-7246
    • Department of Chemical Engineering & Materials Science, University of Minnesota, Minneapolis, MN 55455 (USA), Fax: (+1) 612-626-7246
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  • Funding was provided by the Center for Nanostructured Applications, the Amundson Chair Fund at University of Minnesota, and the NSF (CBET 0956601). Parts of this work were carried out in the Institute of Technology Characterization Facility, University of Minnesota, which receives support from NSF through the NNIN program. Computational support from the Minnesota Supercomputing Institute (MSI) is gratefully acknowledged.

Abstract

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Deposition under control: Silica nanoparticles with finely controllable size and surface charge were synthesized under benign conditions. By adjusting the electrostatic interactions, the silica nanoparticles can be assembled onto inorganic and biological surfaces in a controllable fashion. Potential uses for cell encapsulation are demonstrated.

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