Deacylative Allylation of Nitroalkanes: Unsymmetric Bisallylation by a Three-Component Coupling


  • This research was supported by the National Institute of General Medical Sciences (NIGMS 1R01M079644).


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Use it and lose it! Allylic alcohols were used directly for the synthesis of diallylated nitroalkanes in a three-component coupling based on the strategy of deacylative allylation for the in situ generation of a nucleophile and an allyl electrophile (see scheme).