Get access

Chromatographic Separation of Highly Soluble Diamond Nanoparticles Prepared by Polyglycerol Grafting


  • We thank the Tomei Diamond Co. for providing us with diamond nanoparticles and T. Yamamoto (Shiga University of Medical Science) for assistance with STEM measurements. This research was supported financially by the Science and Technology Incubation Program in Advanced Regions (JST), the Industrial Technology Research Grant Program (NEDO), and a Grant-in-Aid for Challenging Exploratory Research (JSPS).


original image

Making even tiny diamonds valuable: Nanodiamonds (NDs) were covalently functionalized with hyperbranched polyglycerol (PG) by ring-opening polymerization to improve their suitability for biomedical applications (see scheme). The PG-grafted NDs were highly soluble not only in pure water (>20 mg mL−1), but also in a buffer (>16 mg mL−1), and were separated according to size by size-exclusion chromatography.