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Iridium-Mediated Borylation of Benzylic C[BOND]H Bonds by Borohydride


  • We thank the EPSRC for funding and for access to the National Mass Spectrometry facility, Swansea University.


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Simple source: An intramolecular iridium-mediated C[BOND]H borylation proceeds through transfer of a BH3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH4 is thus utilized as the boron source in C[BOND]H to C[BOND]B conversion.