From Noble Metal to Nobel Prize: Palladium-Catalyzed Coupling Reactions as Key Methods in Organic Synthesis

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Abstract

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Building bridges: Palladium-catalyzed cross-coupling reactions of aryl halides and related compounds allow the expeditious and controlled synthesis of important carbon-based scaffolds (see scheme). Their essential role in organic chemistry has resulted in such reactions being recognized by the Nobel Prize for Chemistry 2010.

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