We are grateful to the U.S. National Institutes of Health for continuous support (R01 GM055237 to M.E. and R01 GM071461 to E.R.). Vanderbilt University is a member institution of LS-CAT at the APS, Argonne, IL. Use of the APS at Argonne National Laboratory was supported by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, under Contract No. DE-AC02-06CH11357. siRNA=small interfering RNA.
Unique Gene-Silencing and Structural Properties of 2′-Fluoro-Modified siRNAs†
Version of Record online: 31 JAN 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 10, pages 2284–2288, March 1, 2011
How to Cite
Manoharan, M., Akinc, A., Pandey, R. K., Qin, J., Hadwiger, P., John, M., Mills, K., Charisse, K., Maier, M. A., Nechev, L., Greene, E. M., Pallan, P. S., Rozners, E., Rajeev, K. G. and Egli, M. (2011), Unique Gene-Silencing and Structural Properties of 2′-Fluoro-Modified siRNAs. Angew. Chem. Int. Ed., 50: 2284–2288. doi: 10.1002/anie.201006519
- Issue online: 24 FEB 2011
- Version of Record online: 31 JAN 2011
- Manuscript Received: 17 OCT 2010
- U.S. National Institutes of Health. Grant Numbers: R01 GM055237, R01 GM071461
- U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences. Grant Number: DE-AC02-06CH11357
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