Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

Authors

Errata

This article is corrected by:

  1. Errata: Corrigendum: Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs) Volume 50, Issue 18, 4038, Article first published online: 20 April 2011

  • This work was supported by the Deutsche Forschungsgemeinschaft (FOR 630) and the Fonds der Chemischen Industrie (doctorate stipend to S.R. and a Liebig fellowship to S.A.)

Abstract

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Molecular hazardous materials transport: Enzyme-triggered CO-releasing molecules (ET-CORMs) offer new options for the delivery of CO. The cleavage of dienylester iron tricarbonyl complexes by an esterase under mild oxidative conditions generates CO, which causes a strong inhibiting activity of the compounds to inducible nitric oxide synthase as shown in a cellular assay.

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