• Open Access

Site-Specific Assembly of DNA-Based Photonic Wires by Using Programmable Polyamides


  • G.A.B. thanks the EPSRC (Advanced Fellowship EP/E055095/1), the Royal Society (International Joint Project), and the Wellcome Trust (equipment fund grant) for financial support.


original image

Relay race: The first example of a programmable DNA photonic wire is reported utilizing fluorophore-tethered pyrrole-imidazole polyamides for site-directed fluorophore assembly along a pre-formed DNA duplex (see scheme; PB=Pacific Blue, Cy3=Cyanine 3; orange rectangles=fluorophore). The importance of such control is revealed by efficient energy transport over distances in excess of 27 nm.