Communication

Specific Blocking of CREB/DNA Binding by Cyclometalated Platinum(II) Complexes †

  1. Ping Wang1,‡,
  2. Dr. Chung-Hang Leung1,‡,
  3. Dr. Dik-Lung Ma1,2,
  4. Dr. Raymond Wai-Yin Sun1,
  5. Dr. Siu-Cheong Yan1,
  6. Dr. Qing-Shou Chen1,
  7. Prof. Dr. Chi-Ming Che1,*

Article first published online: 18 FEB 2011

DOI: 10.1002/anie.201006887

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 50, Issue 11, pages 2554–2558, March 7, 2011

Additional Information

How to Cite

Wang, P., Leung, C.-H., Ma, D.-L., Sun, R. W.-Y., Yan, S.-C., Chen, Q.-S. and Che, C.-M. (2011), Specific Blocking of CREB/DNA Binding by Cyclometalated Platinum(II) Complexes . Angew. Chem. Int. Ed., 50: 2554–2558. doi: 10.1002/anie.201006887

Author Information

  1. 1

    Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong (P.R. China), Fax: (+852) 2857-1586

  2. 2

    Present address: Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong (P.R. China)

  1. ‡

    These authors contributed equally to this work.

*Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong (P.R. China), Fax: (+852) 2857-1586

  1. †

    This work was supported by the Area of Excellence Scheme established under the University Grants Committee of the Hong Kong Special Administrative Region, China (AoE/P-10/01), The University of Hong Kong (University Development Fund), and the Innovation Technology Fund (ITS/134/09FP) administrated by the Innovation Technology Commission of the Hong Kong Special Administrative Region, China. CREB=cAMP response element binding protein.

  2. ‡

    These authors contributed equally to this work.

Publication History

  1. Issue published online: 2 MAR 2011
  2. Article first published online: 18 FEB 2011
  3. Manuscript Received: 3 NOV 2010

Funded by

  • University Grants Committee of the Hong Kong Special Administrative Region, China. Grant Number: AoE/P-10/01
  • The University of Hong Kong (University Development Fund)
  • Innovation Technology Fund. Grant Number: ITS/134/09FP
  • Innovation Technology Commission of the Hong Kong Special Administrative Region, China

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