This work was financially supported by NSFC (Nos. 20973182, 20872145, and 20733006), the Chinese Academy of Sciences, 973 Projects (2006CB806200 and 2007CB936401), and NSF (CHE-0805547).
Morphological Transformation between Nanofibers and Vesicles in a Controllable Bipyridine–Tripeptide Self-Assembly†
Article first published online: 15 FEB 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 16, pages 3715–3719, April 11, 2011
How to Cite
Ke, D., Zhan, C., Li, A. D. Q. and Yao, J. (2011), Morphological Transformation between Nanofibers and Vesicles in a Controllable Bipyridine–Tripeptide Self-Assembly. Angew. Chem. Int. Ed., 50: 3715–3719. doi: 10.1002/anie.201006897
- Issue published online: 5 APR 2011
- Article first published online: 15 FEB 2011
- Manuscript Received: 3 NOV 2010
- NSFC. Grant Numbers: 20973182, 20872145, 20733006
- Chinese Academy of Sciences, 973 Projects. Grant Numbers: 2006CB806200, 2007CB936401
- NSF. Grant Number: CHE-0805547
- morphological transformation;
Tuning structures: Stimulus-responsive peptide self-assembly requires a balance of conformational change and structural continuity of stable β sheets. In an amphiphilic bipyridine–tripeptide model, temperature, and ultrasound switch a reversible morphological transformation between vesicles and nanofibers (see picture) through the synergistic effects of terminal β-sheet-forming peptides, flexible linkers, and rotatable bipyridine groups.