A glimpse of light is all it takes: Polymers that undergo main-chain scission at remarkably low photolysis energies were developed as efficient photodegradable substrates for safe laser-mediated cell detachment and patterning. The polymers, which contain acetal or ketal units in their backbone along with suitable absorbing groups, underwent fast degradation to release live cells upon irradiation with an excimer laser (see picture).
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