Introducing A Podand Motif to Alkyne Metathesis Catalyst Design: A Highly Active Multidentate Molybdenum(VI) Catalyst that Resists Alkyne Polymerization

Authors

  • Dr. Kuthanapillil Jyothish,

    1. Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309 (USA), Fax: (+1) 303-492-5894
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  • Prof. Dr. Wei Zhang

    Corresponding author
    1. Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309 (USA), Fax: (+1) 303-492-5894
    • Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309 (USA), Fax: (+1) 303-492-5894
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  • We thank Prof. Cort Pierpoint for help with X-ray structure analysis, Dr. Richard Shoemaker for assistance with NMR spectroscopy, and the University of Colorado for the funding support through the innovative seed grant program.

Abstract

original image

Podand prevents polymers: The molybdenum(VI) propylidyne catalyst 1 with a podand triphenolamine ligand shows high activity in the metathesis of a variety of alkyne substrates, including heterocycles that contain donor moieties. With one substrate-binding site blocked by the multidentate ligand, the undesired polymerization of small alkynes that occurs with non-podand-ligand complex 2 is completely inhibited.

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