SEARCH

SEARCH BY CITATION

Keywords:

  • acetylides;
  • C[BOND]C coupling reactions;
  • Claisen rearrangement;
  • Diels–Alder reaction;
  • natural product synthesis
Thumbnail image of graphical abstract

In a flash: The total synthesis of transtaganolide and basiliolide natural products is achieved in three steps from achiral, monocyclic esters (see scheme). Featured in the syntheses are an Ireland-Claisen/Diels–Alder cascade and a novel methoxyacetylide coupling/cyclization sequence.