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Keywords:

  • biosynthesis;
  • drug delivery;
  • calcium carbonate;
  • heavy-metal extraction;
  • yeast cells
Thumbnail image of graphical abstract

Growing within: The reaction of added Ca2+ ions with the CO2 produced by respiration results in the endogenous production of a CaCO3 scaffold in functionalized cells (see picture). These cells act as anticancer drug carriers with pH-sensitive release, and can enhance the cytotoxicity of drugs by increasing the cellular uptake. The functionalized cells also have potential applications in heavy-metal extraction.