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Keywords:

  • data acquisition;
  • NMR spectroscopy;
  • non-uniform sampling;
  • protein structures;
  • structure elucidation
Thumbnail image of graphical abstract

High-quality multidimensional NMR spectra can be obtained from rapidly recorded non-uniformly sampled (NUS) data. The inherent loss of the spectrum quality usually associated with NUS data is compensated by compressed sensing (CS); left spectrum: Nyquist–Shannon sampling, 22 h acquisition time, Fourier transform; right: CS non-linear sampling, 8.5 h acquisition time, Ip norm minimization.