These authors contributed equally to this work.
Cover Picture: Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers (Angew. Chem. Int. Ed. 13/2011)
Article first published online: 4 MAR 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 13, page 2857, March 21, 2011
How to Cite
Wang, S., Liu, K., Liu, J., Yu, Z. T.-F., Xu, X., Zhao, L., Lee, T., Lee, E. K., Reiss, J., Lee, Y.-K., Chung, L. W. K., Huang, J., Rettig, M., Seligson, D., Duraiswamy, K. N., Shen, C. K.-F. and Tseng, H.-R. (2011), Cover Picture: Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers (Angew. Chem. Int. Ed. 13/2011). Angew. Chem. Int. Ed., 50: 2857. doi: 10.1002/anie.201100624
- Issue published online: 15 MAR 2011
- Article first published online: 4 MAR 2011
- cancer diagnosis;
- cell capture;
- circulating tumor cell;
- nanostructured materials
A capture-agent-coated nanostructured substrate is combined with a microfluidic chaotic mixer to give a new-generation technology for cancer diagnosis. In their Communication on page 3084 ff. H.-R. Tseng and co-workers show that with this system it is possible to isolate circulating tumor cells from whole blood with great efficiency, thus opening up opportunities for the early detection of cancer metastasis not possible with existing technologies.