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Keywords:

  • cancer diagnosis;
  • cell capture;
  • circulating tumor cell;
  • microfluidics;
  • nanostructured materials
Thumbnail image of graphical abstract

A capture-agent-coated nanostructured substrate is combined with a microfluidic chaotic mixer to give a new-generation technology for cancer diagnosis. In their Communication on page 3084 ff. H.-R. Tseng and co-workers show that with this system it is possible to isolate circulating tumor cells from whole blood with great efficiency, thus opening up opportunities for the early detection of cancer metastasis not possible with existing technologies.