Gold-Catalyzed Hydroamination of Alkynes and Allenes with Parent Hydrazine


  • We are grateful to the DOE (DE-FG02-09ER16069) for financial support of this research, and to the Japan Society for the Promotion of Science for fellowships (R.K.).


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A diverse array of nitrogen-containing compounds were formed by the addition of hydrazine to alkynes, diynes, enynes, and allenes in the presence of cationic gold(I) complexes with a cyclic (alkyl)(amino)carbene ligand (see scheme; the X-ray crystal structure of the gold–hydrazine complex is shown). This hydroamination is an ideal initial step for the preparation of acyclic and heterocyclic bulk chemicals. Dipp=2,6-diisopropylphenyl.