Facile and Efficient Control of Bioadhesion on Poly(dimethylsiloxane) by Using a Biomimetic Approach

Authors

  • Dr. Windy Mussard,

    1. UMR 168 CNRS, Laboratoire de Physicochimie Curie, Institut Curie, Centre de recherche 26 rue d'Ulm, 75248 Paris Cedex 05 (France)
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  • Dr. Nasreddine Kebir,

    1. UMR 168 CNRS, Laboratoire de Physicochimie Curie, Institut Curie, Centre de recherche 26 rue d'Ulm, 75248 Paris Cedex 05 (France)
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  • Dr. Irène Kriegel,

    1. Département d'anesthésie, réanimation, douleur Institut Curie, Hôpital, 26 rue d'Ulm, 75248 Paris Cedex 05 (France)
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  • Dr. Marc Estève,

    1. Département d'anesthésie, réanimation, douleur Institut Curie, Hôpital, 26 rue d'Ulm, 75248 Paris Cedex 05 (France)
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  • Dr. Vincent Semetey

    Corresponding author
    1. UMR 168 CNRS, Laboratoire de Physicochimie Curie, Institut Curie, Centre de recherche 26 rue d'Ulm, 75248 Paris Cedex 05 (France)
    • UMR 168 CNRS, Laboratoire de Physicochimie Curie, Institut Curie, Centre de recherche 26 rue d'Ulm, 75248 Paris Cedex 05 (France)
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  • This research was supported by the ANR (ANR-07-EMPB-004-01) and the Institut Curie (PIC maladies nosocomiales).

Abstract

original image

An antiadhesive nanofilm has been designed and prepared in one step in water onto commercial poly(dimethylsiloxane) (PDMS) by mimicking the external region of cell membranes. The resulting biomimetic surfaces are effective in suppressing protein adsorption as well as bacterial and mammalian cell adhesion.

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