Photocontrol of Contracting Muscle Fibers

Authors


  • This work was supported by the VW Stiftung.

Abstract

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A twitch in time: Light-directed inhibition of the interaction between α-1-syntrophin and neuronal NO synthase (nNOS) in living skeletal muscle with a cell-permeable photoswitchable nNOS-derived peptide ligand results in photocontrol of muscle performance and nitric oxide signaling.

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