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Cover Picture: Enantioselective Construction of Quaternary Stereogenic Centers from Tertiary Boronic Esters: Methodology and Applications (Angew. Chem. Int. Ed. 16/2011)



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The combination of two reactions lithiation/borylation and subsequent one-carbon homologation or vinylation to deliver functionalized compounds having quaternary centers in very high enantioselectivity is described by V. Aggarwal et al. in their Communication on page 3760 ff. Bristol's International Balloon Festival and the Clifton suspension bridge act as the backdrop of this chemistry.