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Keywords:

  • biomaterials;
  • click chemistry;
  • coatings;
  • polymers;
  • surfaces
Thumbnail image of graphical abstract

Double “click”: Two different molecules can be sequentially immobilized on defined areas of the same surface by utilizing the different reactivity of activated and non-activated alkynyl groups (see picture). The reactions were carried out at room temperature in water, with the first immobilization step being catalyst-free and the second step requiring CuI as a catalyst.