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Organocatalysis and C[BOND]H Activation Meet Radical- and Electron-Transfer Reactions

Authors

  • Prof. Armido Studer,

    Corresponding author
    1. Organisch-Chemisches Institut, Westfälische Wilhelms-Universität, Corrensstrasse 40, 48149 Münster (Germany)
    • Organisch-Chemisches Institut, Westfälische Wilhelms-Universität, Corrensstrasse 40, 48149 Münster (Germany)
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  • Prof. Dennis P. Curran

    Corresponding author
    1. Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260 (USA)
    • Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260 (USA)
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  • We thank the Deutsche Forschungsgemeinschaft (DFG) and the US National Science Foundation (NSF) for funding. Achim Bruch and Sebastian Wertz are acknowledged for conducting control experiments.

Abstract

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A radical outlook: Recently published “organocatalytic C[BOND]H activation reactions” have now been interpreted as base-promoted homolytic substitutions. The addition of an aryl radical to an arene followed by deprotonation (see above) and electron transfer form part of the chain reaction. Although these new results are not conceptual breakthroughs, they could be experimental breakthroughs because they presage new transformations in radical (anion) chemistry.

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