These authors contributed equally to this work.
Generation of Hot Spots with Silver Nanocubes for Single-Molecule Detection by Surface-Enhanced Raman Scattering†
Article first published online: 3 MAY 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 24, pages 5473–5477, June 6, 2011
How to Cite
Rycenga, M., Xia, X., Moran, C. H., Zhou, F., Qin, D., Li, Z.-Y. and Xia, Y. (2011), Generation of Hot Spots with Silver Nanocubes for Single-Molecule Detection by Surface-Enhanced Raman Scattering . Angew. Chem. Int. Ed., 50: 5473–5477. doi: 10.1002/anie.201101632
This work was supported in part by a research grant from the NSF (DMR-0804088) and a 2006 Director’s Pioneer Award from the NIH (DP1 OD000798). Part of the research was performed at the Nano Research Facility, a member of the National Nanotechnology Infrastructure Network (NNIN), which is supported by the NSF under ECS-0335765.
- Issue published online: 1 JUN 2011
- Article first published online: 3 MAY 2011
- Manuscript Received: 5 MAR 2011
- NSF. Grant Number: DMR-0804088
- NIH. Grant Number: DP1 OD000798
- NSF. Grant Number: ECS-0335765
- single-molecule detection;
- surface-enhanced Raman scattering;
- surface plasmon resonance
Getting hotter: Hot spots that enable detection of surface-enhanced Raman scattering (SERS) from a single molecule can form at the nanocube–substrate interface by simply depositing a silver nanocube onto a metal substrate (see picture). This new approach offers great simplicity for the formation of robust and fully accessible hot spots, thus providing an effective platform for ultrasensitive detection.