We thank the EPSRC and BBSRC for funding.
Screening of a Combinatorial Homing Peptide Library for Selective Cellular Delivery†
Article first published online: 17 MAY 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 27, pages 6133–6136, June 27, 2011
How to Cite
Svensen, N., Díaz-Mochón, J. J., Dhaliwal, K., Planonth, S., Dewar, M., Armstrong, J. D. and Bradley, M. (2011), Screening of a Combinatorial Homing Peptide Library for Selective Cellular Delivery. Angew. Chem. Int. Ed., 50: 6133–6136. doi: 10.1002/anie.201101804
- Issue published online: 21 JUN 2011
- Article first published online: 17 MAY 2011
- Manuscript Received: 14 MAR 2011
- drug delivery;
- homing peptides;
- peptide nucleic acids;
To the point: The identification of peptides to optimize both the delivery and tumor penetration of existing cancer drugs in a cell-selective manner would be highly desirable. The screening of a peptide nucleic acid (PNA)-encoded peptide library (see picture) now allows the identification of versatile cell homing peptides for any cell type of interest.