This work was financially supported by Grant-in-Aid for Scientific Research (S) from the JSPS. T.M. thanks the JSPS for a predoctoral fellowship. Dr. M. Shiro is gratefully acknowledged for X-ray crystallographic analysis of 3 a.
La/Ag Heterobimetallic Cooperative Catalysis: A Catalytic Asymmetric Conia-Ene Reaction†
Article first published online: 6 JUN 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 50, Issue 33, pages 7616–7619, August 8, 2011
How to Cite
Matsuzawa, A., Mashiko, T., Kumagai, N. and Shibasaki, M. (2011), La/Ag Heterobimetallic Cooperative Catalysis: A Catalytic Asymmetric Conia-Ene Reaction. Angew. Chem. Int. Ed., 50: 7616–7619. doi: 10.1002/anie.201102114
- Issue published online: 5 AUG 2011
- Article first published online: 6 JUN 2011
- Manuscript Received: 25 MAR 2011
- cooperative catalysis;
- heterobimetallic complexes;
- homogeneous catalysis;
A dual catalyst system: The cooperative function of a hard and soft Lewis acid (LaIII and AgI, respectively) in a catalyst system that includes an amide-based ligand 1 is crucial for simultaneous activation of intramolecular 1,3-dicarbonyl and alkyne moieties to afford enantioenriched cyclopentane derivatives (see scheme).