Cover Picture: Micromachine-Enabled Capture and Isolation of Cancer Cells in Complex Media (Angew. Chem. Int. Ed. 18/2011)

Authors

  • Dr. Shankar Balasubramanian,

    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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    • These authors contributed equally to this work.

  • Daniel Kagan,

    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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    • These authors contributed equally to this work.

  • Che-Ming Jack Hu,

    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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  • Dr. Susana Campuzano,

    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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  • Dr. M. Jesus Lobo-Castañon,

    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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  • Nicole Lim,

    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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  • Dae Y. Kang,

    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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  • Maria Zimmerman,

    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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  • Dr. Liangfang Zhang,

    Corresponding author
    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
    • Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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  • Prof. Joseph Wang

    Corresponding author
    1. Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
    • Department of NanoEngineering, University of California—San Diego, La Jolla, CA 92093 (USA), Fax: (+1) 858-534-9553
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Abstract

original image

Antibody-functionalized microengine rockets can selectively capture and transport pancreatic cancer cells in complex biological media. In their Communication on page 4161 ff., Zhang, Wang, and co-workers report that these microrockets recognize individual cancer cells from a cell mixture with high selectivity. This strategy holds promise for the design of bioanalytical protocols and microchip devices for early-stage tumor cell detection.

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