SEARCH

SEARCH BY CITATION

Keywords:

  • auxiliaries;
  • benzoic acids;
  • C[BOND]H activation;
  • fluorination;
  • weak coordination
Thumbnail image of graphical abstract

Finally, a choice! A highly selective palladium(II)-catalyzed ortho-monofluorination reaction has been achieved for the first time through a weak coordination (see scheme; Ar=2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl). Simple modification of this protocol allows for a choice between mono- and difluorination. The mono- and difluorinated benzoic acid derivatives are valuable in the pharmaceutical and agrochemical industries.