We thank the European Research Council (ERC) under the European Community’s Seventh Framework Programme (FP7/2007-2013) ERC grant agreement no. 227763 for financial support. The Alexander von Humboldt Foundation is gratefully acknowledged for a research grant to A.J. We also thank BASF AG (Ludwigshafen), W. C. Heraeus GmbH (Hanau), and Chemetall GmbH (Frankfurt) for the generous gift of chemicals.
1521-3773/asset/2002_left.gif?v=1&s=ac6b0d94a94d7ce7a210002b8096b42feffc0bcf)
1521-3773/asset/2002_right.gif?v=1&s=451042aa3415ae3ad0729984d26dee1866aca82e)
Communication
Practical One-Pot Preparation of Magnesium Di(hetero)aryl- and Magnesium Dialkenylboronates for Suzuki–Miyaura Cross-Coupling Reactions†
Article first published online: 24 JUN 2011
DOI: 10.1002/anie.201103022
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Haag, B. A., Sämann, C., Jana, A. and Knochel, P. (2011), Practical One-Pot Preparation of Magnesium Di(hetero)aryl- and Magnesium Dialkenylboronates for Suzuki–Miyaura Cross-Coupling Reactions. Angew. Chem. Int. Ed., 50: 7290–7294. doi: 10.1002/anie.201103022
- †
Publication History
- Issue published online: 25 JUL 2011
- Article first published online: 24 JUN 2011
- Manuscript Received: 2 MAY 2011
Funded by
- European Research Council (ERC). Grant Numbers: FP7/2007-2013, 227763
- Alexander von Humboldt Foundation
Keywords:
- boron;
- boronate;
- cross-coupling;
- magnesium;
- palladium
Mg for B: An atom-economical one-pot synthesis by direct magnesium insertion in the presence of B(OBu)3 and LiCl allows a broad range of functionalized (hetero)aryl and alkenyl bromides to be converted into magnesium diorganoboronates 2, which undergo Suzuki–Miyaura cross-coupling reactions with various aryl (pseudo)halides (see scheme). Both aryl groups of 2 are transferred and furnish the products in good to excellent yields.