Get access

Precision Synthesis of Biodegradable Polymers


  • C.M.T. is grateful to the ENSCP, the CNRS, and the French Ministry of Higher Education and Research for financial support. J.F.L. gratefully acknowledges the CNRS, the University of Strasbourg, the International Center for Frontier Research in Chemistry (FRC, Strasbourg), and the European Research Council (Project SEQUENCES—ERC grant agreement 258593) for financial support.


original image

It′s all in the sequence: The primary structure of poly(lactic-co-glycolic acid) (PLGA), a member of the most widely used class of biodegradable polymers employed in biomedical applications, is demonstrated to strongly influence its degradation properties. Experimental studies evidenced the beneficial effect of ordered monomer sequences on the material properties (see picture).