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Direct Asymmetric α-Allylation of Aldehydes with Simple Allylic Alcohols Enabled by the Concerted Action of Three Different Catalysts

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Errata

This article is corrected by:

  1. Errata: Corrigendum: Direct Asymmetric α-Allylation of Aldehydes with Simple Allylic Alcohols Enabled by the Concerted Action of Three Different Catalysts Volume 51, Issue 21, 5031, Article first published online: 15 May 2012

  • We thank A. Lee for kindly donating several racemic aldehydes and M. W. Alachraf for MS studies. Generous funding by the Max Planck Society is gratefully acknowledged.

Abstract

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Triple catalysis: The title reaction between α-branched aldehydes and allylic alcohols, which generates all-carbon quaternary stereogenic centers, constitutes the first asymmetric Tsuji–Trost-type α-allylation of carbonyl compounds with allylic alcohol (see scheme). This reaction is catalyzed by three different species, [Pd(PPh3)4], the chiral Brønsted acid TRIP, and benzhydryl amine.

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