SEARCH

SEARCH BY CITATION

Keywords:

  • DNA repair;
  • peptide nucleic acids;
  • photoactivation;
  • photolyases;
  • psoralens
Thumbnail image of graphical abstract

Psoralen-derived photolesions are efficiently repaired by a photolyase-like mechanism. The removal of the interstrand crosslink by photoelectron injection confers control over biochemical processes by light (see picture). This paves the way to new, site-selective uncaging applications, as demonstrated with a primer extension assay.