Stepwise Chemically Induced Cardiomyocyte Specification of Human Embryonic Stem Cells

Authors

  • Dr. Rodolfo Gonzalez,

    1. Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA)
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  • Dr. Jae Wook Lee,

    1. Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA)
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  • Prof. Peter G. Schultz

    Corresponding author
    1. Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA)
    • Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA)
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  • This work was supported by the CIRM Training Grant II TG2-01165 (R.G.)

Abstract

original image

Cellular differentiation: Using a high-throughput imaged-based screen a chemical cocktail that promotes efficient human pluripotent cells (hESCs) differentiation into cardiomyocytes was identified.

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