Iridium-Catalyzed Reactions of ω-Arylalkanols to α,ω-Diarylalkanes

Authors

  • Dr. Yasushi Obora,

    Corresponding author
    1. Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, and ORDIST, Kansai University, Suita, Osaka 564-8680 (Japan)
    • Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, and ORDIST, Kansai University, Suita, Osaka 564-8680 (Japan)
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  • Yuka Anno,

    1. Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, and ORDIST, Kansai University, Suita, Osaka 564-8680 (Japan)
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  • Ryuhei Okamoto,

    1. Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, and ORDIST, Kansai University, Suita, Osaka 564-8680 (Japan)
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  • Toyomi Matsu-ura,

    1. Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, and ORDIST, Kansai University, Suita, Osaka 564-8680 (Japan)
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  • Prof. Dr. Yasutaka Ishii

    Corresponding author
    1. Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, and ORDIST, Kansai University, Suita, Osaka 564-8680 (Japan)
    • Department of Chemistry and Material Engineering, Faculty of Chemistry, Materials and Bioengineering, and ORDIST, Kansai University, Suita, Osaka 564-8680 (Japan)
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  • This work was supported by a Grant-in-Aid for Scientific Research (MEXT), the Strategic Project to Support the Formation of Research Bases at Private Universities (2010-2014), matching fund subsidy from the MEXT, and the Kansai University Research Grants: Grant-in-Aid for Encouragement of Scientists, 2011.

Abstract

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The long and the short of it: An atom-economical route to α,ω-diarylalkanes from ω-arylalkanols was achieved by a direct one-step method, or a sequential two-step method depending on the alkyl chain length. The reaction proceeded through the formation of β-methylhydroxy-α,ω-diarylalkanes by dehydrogenation/β-alkylation, followed by dehydrogenation/decarbonylation.

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